Polyploidization and Cancer
Lauren M.F. Merlo, Li-san Wang, John W. Pepper (auth.), Randy Y. C. Poon MA, PhD (eds.)Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.
Kategori:
Tahun:
2010
Edisi:
1
Penerbit:
Springer-Verlag New York
Bahasa:
english
Halaman:
151
ISBN 10:
1441961984
ISBN 13:
9781441961983
Nama siri:
Advances in Experimental Medicine and Biology 676
Fail:
PDF, 3.42 MB
IPFS:
,
english, 2010
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